DYNAMICAL SYSTEMS THEORY OF CELLULAR REPROGRAMMING

Dynamical systems theory of cellular reprogramming

In cellular reprogramming, almost all epigenetic memories of differentiated cells are erased by the overexpression of a few genes, resulting in regaining pluripotency, the potential for differentiation.Considering the interplay between oscillatory gene expression and slower epigenetic Parasites modifications, such reprogramming is perceived as an u

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